Influence of the sodium salt of 4- (3-methyl-2okso-2Н-[1,2,4] triazine [2,3-c] quinazolin-6-yl) butyric acid (DSK-38) on the proliferative, alterative phase inflammatory reaction and antipyretic action evaluation in the experiment

  • V.V. Yakubovska
Keywords: DSK-38, diclofenac, proliferative and alterative phase inflammatory, antipyretic effect

Abstract

In experiments on rats it was found that the sodium salt of 4- (3-methyl-2okso-2Н-[1,2,4] triazine [2,3-c] quinazolin-6-yl) butyric acid (DSK-38, 4 mg/kg ) as diclofenac (8 mg/kg), the antiproliferative effect inherent (cotton granuloma model) and the effect on alterative phase inflammatory response (acceleration of healing dermal wounds). Administering DSK-38 to rats on the background of amid pyrogenic reactions as diclofenac, causes antipyretic effect.

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References

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Published
2017-09-29
How to Cite
Yakubovska, V. (2017). Influence of the sodium salt of 4- (3-methyl-2okso-2Н-[1,2,4] triazine [2,3-c] quinazolin-6-yl) butyric acid (DSK-38) on the proliferative, alterative phase inflammatory reaction and antipyretic action evaluation in the experiment. Reports of Vinnytsia National Medical University, 21(1(1), 8-11. Retrieved from https://reports-vnmedical.com.ua/index.php/journal/article/view/61