Assessment of sympathoadrenal system state of organism in persons with primary arterial hypotension
Abstract
Maintenance of blood pressure at optimal levels is ensured through a complex mechanism of nervous and hormonal regulation, including sympathoadrenal system. We make the analysis of the sympathoadrenal system of the organism in patients with primary arterial hypotension by determining urinary catecholamines content and products of their inactivation - vanillylmandelic and homovanillic acid. It has been established that in patients with primary arterial hypotension is a slight decrease in activity of hormonal and mediator chains of sympathoadrenal system, as evidenced by increased urinary excretion of dihydroxyphenylalanine, dopamine against decrease of norepinephrine, epinephrine and end products of their inactivation - vanillylmandelic acid and homovanillic acid. These changes indicate a decrease in the mechanisms of adaptation and resistance of the organism under conditions of disorders of the cardiovascular system.