@article{Sheremta_Osovskaya_2019, title={Structural and hemodynamic changes in the carotid arteries in young healthy individuals with concentric remodeling of the left ventricle and with normal heart geometry}, volume={23}, url={https://reports-vnmedical.com.ua/index.php/journal/article/view/649}, DOI={10.31393/reports-vnmedical-2019-23(3)-02}, abstractNote={<p>Remodeling of the heart and blood vessels is a complex multifactorial process that determines the prognosis of a patient with different cardiovascular pathologies. <em>The aim</em> of this work is to study in a comparative aspect the features of the hemodynamics of the carotid arteries as marker vessels of the elastic type and the daily blood pressure profile in young healthy individuals with concentric remodeling of the left ventricle and with normal heart geometry. The study involved practically healthy individuals from 18 to 42, aged 25.3±0.6 years, 56 (73.7%) men and 20 (26.36%) women. All study participants were divided into two equal groups depending on the value of the relative wall thickness of the left ventricle (RTW) for 38 people: for RTW&gt;0.42 (concentric remodeling of the left ventricle) and for RTW≤0.42 (normal geometry of the left ventricle). The following research methods were used: echocardiography, 24-hour blood pressure monitoring, duplex scanning of the neck vessels. Statistical analysis of the study results was calculated using the methods of variational statistics using the StatSoft complex “Statistica” v.12. Although the average daily values of blood pressure and the degree of its nightly decline in both groups did not differ significantly, the speed of the morning rise and the variability of systolic pressure were significantly higher in patients with concentric remodeling than without it. That is, even in the absence of symptoms of cardiovascular disease and a history of a rise in blood pressure, the hemodynamic factor of a fast morning increase in blood pressure can take part in the formation of changes in the geometry of the heart in practically healthy young people. Changes in the speed-time parameters of blood flow in the common carotid arteries in the absence of wall thickening (intima-media complex) and a parallel increase in the lumen of the internal jugular veins found in the study indicate structural and hemodynamic vascular remodeling associated with concentric remodeling of the left ventricle in young, practically healthy persons.</p&gt;}, number={3}, journal={Reports of Vinnytsia National Medical University}, author={Sheremta, B.V. and Osovskaya, N.Yu.}, year={2019}, month={Sep.}, pages={354-359} }