Individual prediction of development of cervical dental tissue pathology based on the parameters of oral fluid
Annotation. Significant prevalence of cervical lesions of hard dental tissues is the reason for the search for the ways to predict their development that is possible only with an individual approach to solving this problem. The aim of the study is to determine the chemical composition of the patients’ oral fluid with clinically intact hard tissues, cervical caries and wedge-shaped defect, identify its critical values and the subsequent development of the method for individual prediction of the onset of pathology in young people. To accomplish it we used JSM-6490 LV focused beam electron microscope (scanning) to determine the chemical composition of the enamel and dentin of 29 teeth and their longitudinal sections, the chemical composition of the oral fluid of 33 patients who were divided into three groups depending on the state of their hard dental tissues. The approbation of the proposed method was carried out in 45 young people, the results were compared with the data of the clinical examination of 42 patients a year later. To verify the relationship between the variables, the Pearson parametric correlation method was used based on the determination of the Brave-Pearson parametric coefficient (r) with a 95% confidence level. The reliability of the obtained results was evaluated by Student's t-test, the correlation between indicators – by Student’s test using the Z-test (Fisher’s z-test). The level of significance of differences at p≤0.05 was considered statistically significant. It was determined that the values of the Ca+Na+Mg/P coefficient in enamel, dentin and oral fluid significantly differed depending on the state of hard dental tissues (p≤0.05). Moderate and high inverse correlation was revealed between Ca/P and Ca+Na+Mg/P coefficients in cervical enamel and oral fluid (p≤0.05). Obtained results became the basis for the development of the method for individual prediction of the onset of cervical pathology in young people: with the values of the Ca+Na+Mg/P coefficient higher than 22 – a low level, from 11 to 22 – an average level, lower than 11 – a high risk level. Thus, we have proved that the proposed method is informative (the predictive accuracy reaches 85%), its non-invasiveness is the basis for its widespread use. We consider the search for the ways of individual prediction of the development of cervical caries and wedge-shaped defect in young people based on the parameters of the oral fluid to be promising.
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