Does every family couple that being treated with assisted reproductive technologies need to use preimplantation genetic testing for aneuploidy (PGT-A)?


  • O. L. Lyovkina National Pirogov Memorial Medical University, Vinnytsya, Ukraine
  • S. S. Derii National Pirogov Memorial Medical University, Vinnytsya, Ukraine
  • Y. R. Kuzmenko National Pirogov Memorial Medical University, Vinnytsya, Ukraine
Keywords: Assisted reproductive technologies (ART), euploid embryos, aneuploid embryos, mosaic embryos, in vitro fertilization (IVF), PGT-A

Abstract

The increase in the frequency of using assisted reproductive technologies (ART) dictates the need for pre-implantation diagnosis of embryos to determine which of them are euploid and recommended for embryo transfer (ET), since the main cause of implantation failures when using in vitro fertilization (IVF) is ET aneuploid or mosaic ETs or mosaic imitations that use in vitro fertilization (IVF) is ET aneuploid or mosaic imitative failures when using in vitro fertilization (IVF) is ET aneuploid or mosaic imitations. . For this purpose, the PGT-A technology was created, since the appearance of which and its further development there have been discussions about the feasibility of using PGT-A for each pair, which turned to the use of ART. The purpose of this literature review is to describe the current status of PGT-A and determine the prospects for its widespread adoption in the practice of reproductive medicine. A literature search was carried out in the PubMed and Cochrane databases for the last 10 years. An analysis of the literature has shown that IVF with PGT-A technology has significant advantages over traditional IVF; The technology has a number of technical and financial limitations, which makes it difficult to massively introduce technology into the practice of reproductive medicine, therefore at this stage there should be clear indications for using IVF with PGT-A.

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Published
2019-06-27
How to Cite
Lyovkina, O. L., Derii, S. S., & Kuzmenko, Y. R. (2019). Does every family couple that being treated with assisted reproductive technologies need to use preimplantation genetic testing for aneuploidy (PGT-A)?. Reports of Vinnytsia National Medical University, 23(2), 316-320. https://doi.org/https://doi.org/10.31393/reports-vnmedical-2019-23(2)-25