Indicators of vegetative homeostasis in children with mitral valve prolapse before and after treatment


Keywords: children, mitral valve prolapse, vegetative homeostasis, cardiointervalography

Abstract

For children with mitral valve prolapse (MVP) characterized by disorders of vegetative homeostasis, especially pronounced effect on the body sympathetic link of the autonomic nervous system. In the medical literature, the question of correction of vegetative tone in children with primary MVP is now open. The purpose of the study was to study the parameters of vegetative homeostasis in children with mitral valve prolapse before and after treatment. 66 children with primary and primary MVP stage I and II at the age of 13–17 years were examined. The control group consisted of 23 practically healthy children. The evaluation of vegetative homeostasis was performed using a clinorostatic test and cardiointervalography, followed by an analysis of the parameters and parameters of the heart rate variability spectral analysis. To restore vegetative homeostasis to patients with PMC, an existing treatment regimen with our correction was prescribed. Namely, we added therapies levocarnitine and magnesium. According to the data obtained from the CP, we found that treatment led to the normalization of vegetative maintenance of the organism, mainly in the form of a decrease in the hypersympathicotonic tonic type after treatment, along with the baseline (p<0.05). Consequently, the proposed treatment scheme with the use of levocarnitine and magnesium, positively affects the autonomic system in children with primary MVP, reducing its dysfunction.

Author Biographies

A. V. Kuleshov, National Pirogov Memorial Medical University, Vinnytsya, Ukraine

Ph.D., Associate Professor, Department of Propaedeutics of Pediatrics Diseases with Patient Care, National Pirogov Memorial Medical University

 

 

 

 

 

 

 

 

 

 

 

Y. A. Medrazhevska, National Pirogov Memorial Medical University, Vinnytsya, Ukraine

Ph.D., Associate Professor, Department of Propaedeutics of Pediatrics Diseases with Patient Care, National Pirogov Memorial Medical University

References

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4. Kuleshov, A. V., & Medrazhevskaya, Ya. A. (2019). Klinicheskie osobennosti prolapsa mitralnogo klapana u detej i puti ih korrekcii [Clinical features of mitral valve prolapse in children and methods if it’s correction]. Medicina i farmacevtika: el. nauchnyj zhurnal – Medicine and Pharmaceuticals: e-scientific journal, 1 (2), 8–13.

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Published
2019-06-27
How to Cite
Kuleshov, A. V., & Medrazhevska, Y. A. (2019). Indicators of vegetative homeostasis in children with mitral valve prolapse before and after treatment. Reports of Vinnytsia National Medical University, 23(2), 234-237. https://doi.org/https://doi.org/10.31393/reports-vnmedical-2019-23(2)-09