Clinical, epidemiological and laboratory features of acute brucellosis in the Republic of Azerbaijan
Brucellosis is one of the most common zoonotic infections in the world with a high percentage of chronic forms, which respectively negatively affects the economic component of health systems in countries with high prevalence of brucellosis. The purpose of our study was to determine the clinical, epidemiological and laboratory features of acute brucellosis in the Republic of Azerbaijan. We were screened 178 patients with acute brucellosis who applied for medical services at the Baku Clinic and the Central Clinical Hospital in Baku. Specific methods of the study were conducted by ELISA with the detection of IgM and IgG. Statistical processing the results of the study was performed using the programs “SPSS 20.0”, “STATISTICA 6.0”. Among brucellosis patients, men (75.00%) of the young age (65.00%) who live in rural areas prevail. It was found that in 7.5 times more acute brucellosis was observed among women aged 40–49 years (p<0.05), whereas in the group under 19 years of age, brucellosis was not detected in women. The dominant ways of infection were: contact — in 45.00% of patients with acute brucellosis and alimentary — in 32.5% of people. Among the study group of patients with acute brucellosis, the most frequent clinical symptoms that attracted attention were fever — 86.67%, general weakness — 87.50%), sweating — 70.00%, and arthralgia — 64.17%. While the least of all patients indicated myalgia and body weight loss — 25.83% of individuals. We found that sacroiliitis and peripheral arthritis were 15.8 and 12 times more likely to occur in women than men (p<0.05). The main changes in the general analysis of blood and biochemical analysis are anemia (53.33%), elevated ESR (72.50%), elevation of ALT and AST (35.83% and 40.00% respectively).
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