Results of 3-D reconstruction in dynamic analysis for determining the bone tissue density of the maxilla in human prenatal ontogenesis
The quality of the bone tissue of the jaw bones is of special significance since it is characterized by the pronounced age dynamics and depends both on the course of the mineralization of the skeleton as a whole, and on the specifics of the mineral content of the bone tissue of the particular jaws. The aim is to find out the peculiarities of bone density (MO Hu) in various anatomical areas of the germs of the human maxillary jaw in the dynamics of prenatal ontogenesis using computed tomography and standardized software i-CATVision. The study has been conducted using macroscopy, morphometry, computed tomography, and statistical analysis. The study of the germs of the maxilla in prenatal ontogenesis confirms the asynchrony of density, which is directly proportional to its mineralization, between the right and left sides, which is most pronounced in the alveolar, malar and palatal ridges. Mineral saturation of bone tissue, which reflects its density (MO Hu), is an interdependent coefficient of ratio to its growth rate (%). Alveolar ridges maintain a stable, non-correlated dynamic growth sequence in all experimental age groups, in the frontal area, with a rate of density increase (%) up to 30 weeks of prenatal ontogenesis. The highest density factor of the malar ridges accounts for the 11–16 weeks of the development of the fetus, in the percentage distribution of mineral saturation among the frontal, palatal and alveolar ridges, more than a third of the total value. This analysis forms the idea of the distribution of micro and macro elements that provide bone density, among the stable morphological structures of the maxilla and enriches knowledge with quantitative morphology and becomes a guide for further research and prenatal diagnostics of fetal development as well. We find it promising to carry out the research on mineral content and density of bone tissue of pathologically altered upper jaws of pre-fetuses, human fetuses, newborns and to study their development under conditions of external factors in ecologically unfavorable regions.
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