Dynamics of quality of life in patients with morbid obesity after biliopancreatic diversion and sleeve gastrectomy

  • O.V. Perekhrestenko
Keywords: Morbid obesity, biliopancreatic diversion, sleeve gastrectomy, quality of life


The rapid progress of obesity surgery dictates the necessity to study the quality of life of patients after bariatric procedures. The aim of the study is to assess the dynamics of quality of life of patients with morbid obesity after biliopancreatic diversion in the modification of Hess-Marceau and the sleeve gastrectomy in order to improve the results of surgical treatment of the specified category of patients. The results of surgical treatment of 205 patients with morbid obesity who performed sleeve gastrectomy (main group — 105 patients) or biliopancreatic diversion by Hess-Marceau (comparison group — 100 patients) were analyzed. The study of the dynamics of quality of life of patients was performed in according the Moorehead-Ardelt II method. Statistical data processing was performed using the methods of variational and descriptive statistic using Statistica 6.0 statistical analysis package. Installed that biliopancreatic diversion by Hess-Marceau and sleeve gastrectomy allowed to significantly improve the quality of life of patients with an increase of the quality of life index with -1.5±0.7 in the comparison group and -1.6±0,6 in the main group up to 1.8±0.3 and 2.0±0.4 respectively (p<0.05 compared to pre-operative data) 60 months after surgery. A more pronounced positive dynamics of quality of life in patients of the main group in the time interval of 12–24 months after the operation was achieved due to the absence of severe late metabolic complications and undesirable side effects of biliopancreatic diversion and laparoscopic access for sleeve gastrectomy in 54.3% of patients. Thus, the quality of life of patients with morbid obesity before performing bariatric surgery is critically low and significantly improved after biliopancreatic diversion by Hess-Marceau as well as sleeve gastrectomy. The impact of bariatric surgery on the duration and quality of life of patients requires further multicenter randomized trials.


1. Angrisani, L., Santonicola, A., Iovino, P., Formisano, G., Buchwald, H. & Scopinaro, N. (2015). Bariatric Surgery Worldwide 2013. Obesity Surgery, 25 (10), 1822–32. doi: 10.1007/s11695-015-1657-z.

2. Biter, L. U., van Buuren, M. M. A., Mannaerts, G. H. H., Apers, J. A., Dunkelgrün, M. & Vijgen, G. H. E. J. (2017). Quality of Life 1 Year After Laparoscopic Sleeve Gastrectomy Versus Laparoscopic Roux-en-Y Gastric Bypass: a Randomized Controlled Trial Focusing on Gastroesophageal Reflux Disease. Obesity Surgery, 27 (10), 2557–2565. doi: 10.1007/s11695-017-2688-4.

3. Burgmer, R., Legenbauer, T., Müller, A., de Zwaan, M., Fischer, C. & Herpertz, S. (2014). Psychological outcome 4 years after restrictive bariatric surgery. Obesity Surgery, 24 (10), 1670–8. doi: 10.1007/s11695-014-1226-x.

4. De Luca, M., Angrisani, L., Himpens, J., Busetto, L., Scopinaro, N., Weiner, R. … Shikora, S. (2016). Indications for Surgery for Obesity and Weight-Related Diseases: Position Statements from the International Federation for the Surgery of Obesity and Metabolic Disorders (IFSO). Obesity Surgery, 26 (8), 1659–96. doi: 10.1007/s11695-016-2271-4.

5. Giuliani, A., Migliaccio, C., Ceriello, A., Aragiusto, G., La Manna, G. & Calise, F. (2014). Laparoscopic vs. open surgery for treating benign liver lesions: assessing quality of life in the first year after surgery. Updates Surg. 66 (2), 127–33. PubMed PMID: 24659501.

6. Hachem, A. & Brennan, L. (2016). Quality of Life Outcomes of Bariatric Surgery: A Systematic Review. Obesity Surgery, 26 (2), 395–409. Review. PubMed PMID: 26494369. DOI:10.1007/s11695-015-1940-z.

7. Kolotkin, R. L., Kim, J., Davidson, L. E., Crosby, R. D., Hunt, S. C. & Adams, T. D. (2018). 12-year trajectory of health-related quality of life in gastric bypass patients versus comparison groups. Surgery for Obesity and Related Diseases, pii: S1550-7289 (18), 30244-2. doi: 10.1016/j.soard.2018.04.019.

8. Seidell, J. C. & Halberstadt, J (2015). The global burden of obesity and the challenges of prevention. Annals of Nutrition and Metabolism, 66 (2), 7–12. doi: 10.1159/000375143.

9. Skancke, M., Schoolfield, C., Grossman, R., Kerns, J. C., Abel, N. & Brody, F. (2018). Laparoscopic Sleeve Gastrectomy for Morbid Obesity at a Veterans Affairs Medical Center. J. Laparoendosc. Adv. Surg. Tech. A., 28 (6), 650–655. doi: 10.1089/lap.2018.0002.

10. Study protocol for the World Health Organization project to develop a Quality of Life assessment instrument (WHOQOL). (1993) Quality of Life Research, 2 (2), 153–9.

11. Versteegden, D. P. A., Van Himbeeck, M. J. J. & Nienhuijs, S. W. (2018). Improvement in quality of life after bariatric surgery: sleeve versus bypass. Surg. Obes. Relat. Dis., 14 (2), 170–174. doi: 10.1016/j.soard.2017.10.008.
How to Cite
Perekhrestenko, O. (2018). Dynamics of quality of life in patients with morbid obesity after biliopancreatic diversion and sleeve gastrectomy. Reports of Vinnytsia National Medical University, 22(3), 548-552. https://doi.org/https://doi.org/10.31393/reports-vnmedical-2018-22(3)-32