Effectiveness of preconceptional prevention of gestational complications by using folates


  • V.P. Mishchenko
  • I.V. Rudenko
  • M.Yu. Golubenko
  • N.A. Stamova
Keywords: preconception prevention, gestational complications, folates.

Abstract

Preconceptional prophylaxis is a component of medicine, prevents occurrence of gestational complications, perinatal pathology, including congenital malformations. 30 patients and their husbands were examined who underwent preconception training 3 months prior to fertilization and 30 women without preconception training were examined. Preventing gestational complications, perinatal pathology, including congenital malformations, is advisable to begin at least 3 to 4 months before fertilization. This makes it possible to evaluate the premorbid background of the organisms of future parents, to determine and conduct a pathogenetically substantiated differentiated individualized complex stage full-fledged correction of metabolic disorders, taking into account the possible hereditary disruption of the activity of specific enzymes. The effectiveness of preconception prophylaxis of gestational complications depends both on the timely evaluation of the initial state of the organism of future parents and on the correction of the vitamin content in the body, which contributes to the stabilization of oxidation-reduction processes, folate cycle, balanced exchange of macro- and microelements under the control of the initial and the dynamics of monitoring the levels of these substances. The most modern drug of choice for the correction of the content of vitamins, macro-, microelements, amino acids is the vitamin complex Natalker I-II.

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Published
2018-08-08
How to Cite
Mishchenko, V., Rudenko, I., Golubenko, M., & Stamova, N. (2018). Effectiveness of preconceptional prevention of gestational complications by using folates. Reports of Vinnytsia National Medical University, 22(1), 194-197. https://doi.org/https://doi.org/10.31393/reports-vnmedical-2018-22(1)-37