The impact of open and videolaparoscopic abdominal sanitation on the immune profile of patients with purulent peritonitis
The effect of open and techniques videolaparoscopic repeated abdominal drainage on the immune profile in 126 patients with purulent peritonitis. All patients divided into control (65 patients) and the study group (61 patients). In 14 (21,5%) patients in the control group were did 17 traditional relaparotomy "on-demand" and "programmed" mode. In 12 (19,6%) patients of the study group was performed 5 (8,1%) open relaparotomy "on demand", and 12 (19,6%) laparoscopy, 5 of which were performed in patients with end- stage of peritonitis was combined with directed local immune therapy cykloferon and lipin. Patients of the main group was carried out only one open relaparotomy, 2 and more never performed in any patient. Using of videolaparoscopy in conjunction with a local directed immune therapy allowed to speed up the restoration of normal immune status of patients the main group (observed normalization of CD3, CD4, CD16, CD25, IgG, IgM, IgA, reducing CD19, CD95), shorten hospitalization and reduce postoperative mortality.