Prognostic meaning of index of cardiac age in males with hypertension
The aim of this study was to determine the possibility of applying an index of cardiac age (ICA) for predicting an individual risk in hypertensive males aged 45-65 years. The study included 90 hypertensive patients aged 45-65 years old, males who had irreversible organ damage. The control group consisted of 30 men of the same age without hypertension and lesions of the cardiovascular system. The hypertensive patients were divided into 3 groups of 30 persons depending on the degree of hypertension. All patients underwent office BP measurement, standard echocardiography and definition of ICA - one of the indicators of biological age (BA) of the cardiovascular system. ICA was calculated by the method of H. Masugata H. et al. , which includes a definition of echocardiographic parameters such as the thickness of the interventricular septum in left ventricular outflow tract (VSot) and the angle between the ascending aorta and the interventricular septum (VS-AO). The results showed that there was a significant correlation (p<0,01) between ICA and the degree of hypertension. The biological age of the heart increased with the degree of hypertension. The proportion of patients with premature aging increased in the direction from the normotensive patients to patients with hypertension of the third stage, while the number of those who observed slow aging decreased. Taking into account the informativity and availability of ICA, it can be recommended as a simple method for estimating an individual cardiovascular risk in hypertensive patients.