Particularities of cervical epithelium cytogram in young nulliparous women with endocervicosis
Despite the modern methods of diagnostic and therapeutic techniques in treating cervical diseases, every year 470 thousand new cases are recorded worldwide, 223 thousands of which end fatally. Cohort study included 142 young nulliparous women of 18 - 25 years of age with cervix benign pathology, 112 of which were diagnosed histologically proven endocervicosis. Depending on the chosen method the women were divided into 2 Groups: Group I included 55 patients with endocervicosis, who were treated according to clinical protocols; Group II consisted of 57 nulliparous women with endocervicosis, who were given the proposed treatment method, which included local cervix uteri pathology destruction by means of argon plasma coagulation and use of complex vaginal medication with chlorhexidine and dekspantenol. The Control Group included 30 young nulliparous women with no pathological changes in their exocervix. Cytological diagnosis detected changes characteristic of Class II a in 21,82 % women of Group І and in 17,54 % women of Group II. In 32,73% cases of Group I and in 33.33% cases of Group II varieties of pathological cornification. Cells with characteristic signs of a human papilloma virus were found in cytological specimens in 38,18% of patients in Group I and 40,35% in Group II. Dynamic observation after 3 months showed that type I cytological smear was detected in 83.64% patients in Group I and in 91,22% patients of Group II. Classes II a and II b were found in 9 patients of Group I (16,36%). As for the patients of Group II, satisfactory Papanicolaou smear type I cytograms were reported about at 6 and 12 months periods after treatment. The results of the study demonstrate the high efficiency of combination of pathological focus destruction by means of argon plasma coagulation and use of complex vaginal medication with chlorhexidine and dekspantenol in postoperative period.