Clinical-functional characteristics of ischemic heart disease in connection with diabetes mellitus

  • V.K. Serkova
  • Yu.L. Zadachina
  • O.P. Ivanova
Keywords: coronary heart disease, diabetes mellitus, clinical features of the course, electrocardiography, echocardiography.


The purpose of the study: optimization of coronary heart disease diagnostics in patients with diabetes mellitus (DM) by studying the clinical and functional characteristics of the coronary heart disease course in combination with DM type 2. 112 patients with coronary heart disease were examined, including 66 patients with a combination of coronary heart disease and diabetes and 46 patients with coronary heart disease without manifestations of diabetes. It was established that coronary artery disease at the diabetes mellitus develops at a younger age, is more pronounced and is characterized by a higher incidence and depth of ST segment segmentation, longer episodes of myocardial ischemia and their total daily duration, more frequent painless ischemia of the myocardium. In patients with diabetes mellitus coronary heart disease is often accompanied by a violation of the rhythm (ventricular and supraventricular extrasystoles, supraventricular tachycardia). The combination of diabetes and coronary heart disease increases the degree of pathological myocardial remodeling, mainly due to dilatation of the heart, contributes to the progression of systolic and diastolic dysfunction and increased arrhythmic activity. The absence of a typical clinical picture of coronary heart disease in patients with diabetes promotes later recognition, often at the stage of complications, which leads to the late appointment of adequate therapy.


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How to Cite
Serkova, V., Zadachina, Y., & Ivanova, O. (2017). Clinical-functional characteristics of ischemic heart disease in connection with diabetes mellitus. Reports of Vinnytsia National Medical University, 21(2), 465-469. Retrieved from