Features of influence of cryopreserved human amniotic membrane depending on the type of its fixation on the bacterial keratitis model


  • K.V. Sereda
  • G.I. Drozhzhyna
  • T.B. Gaidamaka
  • V.V. Vit
  • V.A. Shablii
  • G.S. Lobintseva
Keywords: bacterial keratitis, cryopreserved amniotic membrane, experiment

Abstract

The study is important due to insufficient investigation of amniotic membrane transplantation efficiency in bacterial keratitis. The objective was to study in the experiment features of anti-inflammatory action of viable cryopreserved human amniotic membrane on the model of bacterial keratitis using different surgical techniques. Transplantation of viable cryopreserved amniotic membrane was performed in 30 Chinchilla rabbits on the developed model of bacterial keratitis using inlay technique. In one month after transplantation in several rabbits corneal edema infiltration and vascularization were found. At the same depth of the corneal destruction by bacterial infectious process biological covering technique should be preferred as less traumatic surgical intervention, which is accompanied by a lower inflammatory response.

Published
2017-09-29
How to Cite
Sereda, K., Drozhzhyna, G., Gaidamaka, T., Vit, V., Shablii, V., & Lobintseva, G. (2017). Features of influence of cryopreserved human amniotic membrane depending on the type of its fixation on the bacterial keratitis model. Reports of Vinnytsia National Medical University, 20(1(1), 21-27. Retrieved from https://reports-vnmedical.com.ua/index.php/journal/article/view/296