Structural and functional changes of the left ventricle and vessels in the patients with essential hypertension of the 2nd stage depending on the type of the daily profile of arterial pressure


  • T.Yu. Nyushko
Keywords: daily monitoring of arterial pressure, left ventricle remodeling, diastolic dysfunction, endothelial dysfunction

Abstract

2 types of the left ventricular remodeling were established: concentric and eccentric hypertrophy, and 2 types of the AP daily profile: "dipper" and "non-dipper". It was established that patients with the "non-dipper" daily profile as compared to the patients with the "dipper" one had higher AP and greater pressure load on the target organs (average daily SAP 160,16±1,68 mm Hg, average daily DAP 98,57±1,61 mm Hg, daily blood pressure load of SAP 82,24±2,17 %, daily blood pressure load of DAP 69,03±2,05 %, and 148,17±2,09 mm Hg, 92,29±1,83 mm Hg, 68,07±2,36 %, 49,14±2,15 %, respectively, (p<0,05)) that led to more evident structural- geometrical and functional changes of left ventricular (LV myocardium mass index 114,52±1,82 g/m2, E/A 0,79±0,03 m/s and 110,05±2,73 g/m, 0,97±0,20 m/s, respectively). The patients with insufficient night decrease of AP also had more severe structural and functional vessel dysfunctions (EDVD 8,14±0,18 %, EIVD 16,97±0,17 %) as compared to the patients with the "dipper" profile (10,52±0,17%, 18,62±0,14 %, respectively p<0,01)).

Published
2017-09-29
How to Cite
Nyushko, T. (2017). Structural and functional changes of the left ventricle and vessels in the patients with essential hypertension of the 2nd stage depending on the type of the daily profile of arterial pressure. Reports of Vinnytsia National Medical University, 19(2), 379-385. Retrieved from https://reports-vnmedical.com.ua/index.php/journal/article/view/247