Structural changes in human myocardium under conditions of acute ischemia using correlational phase laser analysis
The article describes the main structural changes of the myocardium under conditions of acute coronary insufficiency, obtained by the study of laser polarimetric images by phase laser analysis. Materials. Myocardial tissue slices, which were divided into two groups: 97 samples of myocardium from corpses of people who died as a result of ischemic heart disease and myocardial samples of 94 corpses, who died from acute coronary insufficiency. In this paper, we used the method of phase analysis of laser polarimetric images. The study was performed on a Mach-Zehnder interferometer. We found that under conditions of acute coronary insufficiency and ischemia duration of less than six hours morphological changes in the structure of the myocardium manifest as changes in the structure of the myosin filaments. From the data obtained by experimental studies of the correlation structure of the distributions of the polarization of myocardial tissue samples, the objective possibility of reliable diagnosis of death due to acute coronary insufficiency. The most informative turned out to be correlation moments of the 2nd and 3rd order, characterizing the autocorrelation function of the distribution of values of phase shift laser images of myocardial tissue samples.