Preliminary results of surgical treatment of primary open-angle glaucoma after trabectomy ab interno


  • N.I. Kapshuk
  • L.A. Khrystych
Keywords: trabectomy, glaucoma.

Abstract

In the article we present the effectiveness of the trabectomy ab interno in patients with various stages of open-angle glaucoma. According to the results of our study, it is established that the use of minimally invasive glaucoma surgery ensures a stable decrease in intraocular pressure (IOP) level within 6 months after the operation. Thus, in 15 patients with various stages of open-angle glaucoma (65±7 years), using parametric analysis of dependent groups we obtained a statistically significant difference between the IOP level before and at different periods after trabectomy ab interno (p=0,0001). So, the obtained results testify that trabectomy ab interno is an effective and safe method of reducing IOP level and has several advantages over filtering operations.

References

1. Nesterov, A. P., Bunin, A. Ya. & Kacnelson, L. A. (1974). Vnutriglaznoe davlenie. Fiziologiya i patologiya. Moskva: Nauka. [in Russian].

2. Tomilova, E. V., Hizhnyak, I. V. & Shuhaev, S. V. (2014). Gipotenzivnyj effekt trabekulotomii ab interno, vypolnennoj odnomomentno s fakoemulsifikaciej katarakty. Sovremennaya tehnologii v oftalmologii, 3, 100–103. [in Russian].

3. Cairns, J. E. (1968). Trabeculectomy. Preliminary report of a new method. American Journal of Ophthalmology, 66 (4), 673–9.

4. Fea, A. M. (2010). Phacoemulsification with micro-bypass stent implantation in primary open-angle glaucoma: randomized double-masked clinical trial. Journal of Cataract & Refractive Surgery, 36 (3), 407–412.

5. Francis, B. (2011). Trabectome combined with phacoemuisification versus phacoemulsification alone: a prospective, non-randomized controlled surgical trial. Clinical and Surgical Journal of Ophthalmology, 118 (3), 459–467.

6. Grieshaber, M. C., Grieshaber, H. R. & Stegmann, R. (2016). A New Expander for Schlemm Canal Surgery in Primary Open-angle Glaucoma-Interim Clinical Results. Journal of glaucoma, 25, 657–662.

7. Grieshaber, M. C., Pienaar, A. & Olivier, J. (2010). Clinical Evaluation of the Aqueous Outflow System in Primary Open-Angle Glaucoma for Canaloplasty. Investigative Ophthalmology & Visual Science, 51 (3), 1498–1504.

8. Linner, E. (1989). Aqueous humor outflow pathways following trabeculectomy in patients with glaucoma (in German). Klin. Monatsbl. Augenheilkd., 195, 291–293.

9. Namba, H. (1983). Blood reflux into anterior chamber after trabeculectomy. Jpn. J. Ophthalmol., 27, 616–625.

10. Wilensky, J. T., Zeimer, R. C., Gieser, D. K. & Kaplan, B. H. (1994). The effects of glaucoma filtering surgery on the variability of diurnal intraocular pressure. Trans. Am. Ophthalmol. Soc., 92, 377–383.

11. Wilmsmeyer, S., Philippin, H. & Funk, J. (2006). Excimer laser trabeculotomy: a new, minimally invasive procedure for patients with glaucoma. Graefe’s Archive for Clinical and Experimental Ophthalmology, 244 (6), 670–676.

12. WuDunn, D. A., Cantor, L. B., Palanca-Capistrano, A. M., Hoop, J., Alvi, N. P., Finley, C. … Knotts, S. L. (2002). A prospective randomized trial comparing intraoperative 5–luorouracil vs mitomycin C in primary trabeculectomy. Am. J. Ophthalmol., 134 (4), 521–28.
Published
2017-09-29
How to Cite
Kapshuk, N., & Khrystych, L. (2017). Preliminary results of surgical treatment of primary open-angle glaucoma after trabectomy ab interno. Reports of Vinnytsia National Medical University, 21(2), 433-436. Retrieved from https://reports-vnmedical.com.ua/index.php/journal/article/view/20