Structural and functional changes of the heart in patients with nonviral chronic hepatitis of different age
Age peculiarities of structural and functional parameters of the heart in nonviral chronic hepatitis patients were studied. Mature and elderly patients revealed significant changes in structural and functional parameters of the heart compared to young patients: a progressive increase in the left atrium size by 11,1% and 12,9%, right ventricle diameter - by 6,1% and 5,6%, left ventricle posterior wall thickness in diastole - by 14,4% and 18,3%, interventricular septum thickness in diastole - by 5,9% and 11,9%; significant decrease in ejection fraction by 6,1% and 8,5% respectively. In elderly patients significantly decreased end diastolic and systolic dimensions by 10,9% and 18,6% compared with those in young patients. Left ventricular mass increased by 13,8% and 25,2%, left ventricular myocardial mass index - by 15,8% and 29,6% in elderly and mature patients with chronic hepatitis. The left ventricle geometry also changed, that in young age manifested to concentric remodeling and eccentric hypertrophy of the left ventricle and in mature and elderly patients to increase quantity of people with concentric left ventricular hypertrophy.