The pathomorphological and immunohistochemical features of decidua and chorion in women with tubal pregnancy


  • M.V. Brazhuk
  • V.P. Kondratyuk
  • N.P. Dzis
Keywords: pathomorphology, immunohistochemistry, decidua, chorion, tubal pregnancy

Abstract

A histological and immunohistochemical study of 85 surgical samples of the material (areas of fallopian tube, the fertilized egg, areas of ovaries, decidua, curettage of the uterus) from women with tube pregnancy was make. For ectopic nidation typical is a sharp decrease in proliferative processes in the chorale tissue, as evidenced by the downregulation proliferative marker Ki- 67 in the chorionic villi, combined with a sharp decline or no expression of endothelial factor SD31 in vascular endothelium of chorion structures and of the fallopian tube background of chronic salpingitis, which occurred in 75,3% of cases. These studies have shown the key role of chronic inflammation in the pathogenesis of genital tubal pregnancy.

Published
2017-09-29
How to Cite
Brazhuk, M., Kondratyuk, V., & Dzis, N. (2017). The pathomorphological and immunohistochemical features of decidua and chorion in women with tubal pregnancy. Reports of Vinnytsia National Medical University, 19(1), 62-66. Retrieved from https://reports-vnmedical.com.ua/index.php/journal/article/view/166