Effects of applying defect of the tibia after 60-day administration of sodium benzoate on the growth rate of the skeleton in white rats


  • G.V. Lukyantseva
Keywords: skeleton, bone defect, growth, sodium benzoate, mexidol

Abstract

In the experiment on 280 white rats found that the application of the defect of the tibia after 60-day administration of sodium benzoate is accompanied by slower growth of bones (humeral, hipbone and third lumbar vertebra) compared with the group without administration of sodium benzoate. Under dosage of sodium benzoate of 1000 mg/kg, the severity of the changes was larger than that at a dose of 500 mg/kg. The simultaneous administration of sodium benzoate and mexidol at dosage of 50 mg/kg body weight smoothed growth rate inhibition at investigated bones after application defect of the tibia.

Published
2017-09-29
How to Cite
Lukyantseva, G. (2017). Effects of applying defect of the tibia after 60-day administration of sodium benzoate on the growth rate of the skeleton in white rats. Reports of Vinnytsia National Medical University, 19(1), 34-37. Retrieved from https://reports-vnmedical.com.ua/index.php/journal/article/view/159