The efficiency of therapeutic and prophylactic use of «sorbifer durules»complex and «vitrum prenatal forte» in pregnant women with iron deficiency anemia (IDA) diagnosed with generalized periodontitis (GP)


  • O.G. Boychuk-Tovsta
  • M.M. Rozhko
Keywords: generalized periodontitis, pregnancy, iron deficiency anemia.

Abstract

According to modern classification, anemia in pregnant women should be referred to a mixed form in which IDA is a combination of the deficit and imbalance of trace elements, which in turn is one of the main factors of resistance to monotherapy of patients with iron. Exchange violation IU, high biological activity which is related to the impact on metabolism processes blood, tissue respiration, determine their role in the pathogenesis of many diseases, including paradontitis. The purpose of the study examine the effectiveness of health care complex «Sorbifer Durules» and «Vitrum prenatal forte» in patients with generalized periodontitis of pregnant women with iron deficiency anemia. Evaluated biochemical parameters of blood and oral fluid (transferrin saturation in iron, serum iron, ferritin concentration in serum, the activity of phosphatases in the oral fluid and blood and serum) in patients with GP pregnant women with iron deficiency anemia and somatically healthy pregnant women without GP. Assessing the biochemical parameters of blood serum and oral fluid noted the increase of transferrin saturation with iron in serum, increased serum iron 1.17 times (r˂0,001), the increase of the concentration of serum ferritin 1.4 times (r˂0,001). Treatment contributed regulating the activity of phosphatases. This measure alkaline phosphatase activity in serum increased 1.8 times (r˂0,001), and in oral fluid observed an increase of 1.8 times (r˂0,001). The activity of acid phosphatase in serum decreased in 2 times (r˂0,001), and in oral fluid at 2.75 times (r˂0,001). Using the proposed method GP general medical treatment in pregnant women with IDA improves the general condition, reduce the negative impact of extragenital pathology of periodontal tissue and achieve long-term remission.

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Published
2017-09-29
How to Cite
Boychuk-Tovsta, O., & Rozhko, M. (2017). The efficiency of therapeutic and prophylactic use of «sorbifer durules»complex and «vitrum prenatal forte» in pregnant women with iron deficiency anemia (IDA) diagnosed with generalized periodontitis (GP). Reports of Vinnytsia National Medical University, 21(1(2), 289-292. Retrieved from https://reports-vnmedical.com.ua/index.php/journal/article/view/132