Pathomorphological background of neovasculogenesis as a cause of recurrent varicose veins of the lower extremities
Currently, a leading theory of the development varicose veins recurrence (VVR) on lower extremities which is not associated with surgical tactical and technical errors is a neovasculogenesis theory. The study results allowed to confirm the presence of neovasculogenesis factor in recurrence of varicose veins on lower extremities. The following promising areas in pathomorphological studies of the varicose vein recurrence were identified to optimize the treatment and prevention of relapse: further study of the neovasculogenesis phenomenon; obtaining evidence for the separation of at least two risk groups of recurrent varicose veins of the lower extremities: with genetically determined disorders of elastic fibers, in particular being a part of the venous valves and also through induced neovasculogenesis in the veins walls of various localization, including the groin.
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