Structural changes of rats’ aggregated lymphoid nodules of ileum in an experimental skin burn injury under the conditions of infusion by lactoprotein with sorbitol


  • R.M. Matkivska
Keywords: skin burn injury, infusion therapy, Lactoprotein with sorbitol, structural changes, aggregated lymphoid nodules.

Abstract

With the help of light and electron microscopy it was determined that the general signs of structural changes in aggregated lymphoid nodules of ileum (Peyer’s patch) in rats with the experimental thermal skin injury are necrosis and apoptosis of functionally different cells which occur against the background of significant changes of haemo and lymphatic microvasculature. It is determined that membranoplastic effect of lactoprotein with sorbitol has distinct organ specific traits which present in “exclusion” of range of hemocapillaries from hemomicrocirculatory system due to appearance of circular membrane structure acting as ansa and contributing to vascular lumen closure. It is proved that most damaged hemocapillaries are more transformed and are “excluded” first. It leads to changes in hemomicrocirculation that induce changes in lymphatic microcirculation and relevant changes of selective recirculation of lymphocytes that are not structurally damaged. Considering unsystematic cells aggregation of various immunocytes which are in different functional status and at different stages of responsive and destructive transformation (“overfill” phenomenon) in the lumen of juxta nodules lymph capillaries results in their migration to lymph nodule must be negative as for adequate performance of the immune function.

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Published
2017-09-29
How to Cite
Matkivska, R. (2017). Structural changes of rats’ aggregated lymphoid nodules of ileum in an experimental skin burn injury under the conditions of infusion by lactoprotein with sorbitol. Reports of Vinnytsia National Medical University, 21(2), 385-392. Retrieved from https://reports-vnmedical.com.ua/index.php/journal/article/view/10